Antioxidant activities and GC-MS analysis of essential oil extracted from Salvia officinalis L.

Abstract

Salvia officinalis L., the common sage, is considered to be the most representative species among the Salvia species. The aim of the present study was to evaluate the antioxidant activity and identify the bioactive compounds by performing GC-MS analysis of essential oil extracted from Salvia officinalis. The oil was extracted by employing chloroform as solvent in Soxhlet apparatus. The phytochemical screening was carried out by standard methods which revealed the presence of important phyto constituents such as alkaloids, terpenoids, steroids, and phenolic compounds. The antioxidant assays such as DPPH˙ radical, ABTS˙+ radical cation, OH˙ radical scavenging assays, Phoshomolybdenum reduction and Fe3+ reducing power assays were studied for the essential oil of Salvia officinalis. GC-MS analysis showed the presence of volatile compounds. The IC50 values DPPH˙radical, ABTS˙+ radical cation, OH radical scavenging assays were found to be 10.47, 10.32 and 68.27 µg/mL concentration respectively. The results of this study portray the effective antioxidant activity of S. officinalis.