review Open AccessTop 1% cited
Trends in GPCR drug discovery: new agents, targets and indications
Nature Reviews Drug Discovery · 2017 · Vol. 16(12) · pp. 829–842
Alexander S. Hauser✉(University of Copenhagen)Misty M. Attwood(Uppsala University)Mathias Rask‐Andersen(Science for Life Laboratory)Helgi B. Schiöth(Uppsala University)David E. Gloriam(University of Copenhagen)
Receptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyPancreatic function and diabetesDrug discoveryDrugG protein-coupled receptorComputational biologyMedicinePharmacologyData scienceComputer scienceBioinformaticsBiology
MeSH terms
Allosteric RegulationAnimalsHumansDrug DesignDrug ApprovalReceptors, G-Protein-CoupledDrug DiscoveryMolecular Targeted Therapy
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References
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Nature Reviews Drug Discovery · 2006 · 3,473 citations
G-protein-coupled receptors and signaling networks: emerging paradigms
Trends in Pharmacological Sciences · 2001 · 1,045 citations
Tissue-based map of the human proteome
Science · 2015 · 15,548 citations
Polypharmacology: Challenges and Opportunities in Drug Discovery
Journal of Medicinal Chemistry · 2014 · 1,045 citations
A comprehensive map of molecular drug targets
Nature Reviews Drug Discovery · 2016 · 2,383 citations
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