article Open AccessTop 1% cited
chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data
Nature Methods · 2017 · Vol. 14(10) · pp. 975–978
Alicia N. Schep(Dynamic Systems (United States))Beijing Wu(Dynamic Systems (United States))Jason D. Buenrostro✉(Broad Institute)William J. Greenleaf(Chan Zuckerberg Initiative (United States))
Single-cell and spatial transcriptomicsGenomics and Chromatin DynamicsEpigenetics and DNA MethylationEpigenomicsChromatinComputational biologyR packageTranscription factorAnnotationBiologyComputer scienceCluster analysisGenetics
MeSH terms
AlgorithmsAnimalsCell LineGene Expression RegulationSoftwareTranscription FactorsSequence Analysis, DNAEpigenomics
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References
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
Molecular Cell · 2010 · 14,269 citations
Fast gapped-read alignment with Bowtie 2
Nature Methods · 2012 · 59,710 citations
Model-based Analysis of ChIP-Seq (MACS)
Genome biology · 2008 · 19,514 citations
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