In vitro antioxidant activity and phytochemical screening of Croton zambesicus

Abstract

The present study was designed to investigate the antioxidant activity of C. zambesicus fruits and whole plant. Phytochemical study was piloted to detect the bioactive compounds, which have been responsible for the biological activities. The antioxidant activities were conducted via DPPH radical scavenging assay. Potential antioxidant activity was presented by ethanol crude extract was motivated to evaluate the fractions of hexane, chloroform, ethyl acetate, n-butanol and water, the radical scavenging activities of whole plant were found to be 72 ± 0.03, 79 ± 0.02, 80 ± 0.05, 89 ± 0.01, 85 ± 0.01, 77.3 ± 0.05 respectively, and the fruit extracts were found to be 81 ± 0.03, 41.4 ± 0.01, 51 ± 0.04, 85 ± 0.01, 88 ± 0.02, 77.3 ± 0.01 respectively. The results of phytochemical screening showed the presence of Flavonoids, Saponins, Alkaloid, Tannins, Phenols, Triterpene, Phytosterol, Anthraquinones and Carbohydrates. This study give rise to antioxidant property of studied plant, and showed interesting correlation with the phytochemical constituents and biological activities.