Inhibition and modulation of calcium oxalate monohydrate crystals by phytic acid: An in vitro study

Abstract

The aim of the study was to explore the inhibition and modulation of calcium oxalate monohydrate crystals into calcium oxalate dihydrate by phytic acid. The study was carried out on glass slides by using phytic acid (1 - 5%) solutions. All tested solutions inhibited the growth and modulated calcium oxalate monohydrate crystals. Donuts, rosettes and X-shape crystals of calcium oxalate monohydrate along with their defected forms were observed. Whereas, the presence of calcium oxalate dihydrate crystals as elongated rods and tetragonal bipyramidal crystals revealed the modulated forms of calcium oxalate monohydrate. Smaller zones of nucleation declare as general patterns of growth inhibition. This study gives valuable information about inhibition and modulation pattern of calcium oxalate crystals. Further studies are required to confirm the results of present study.