Evaluation of binding efficacy of starch isolated from Dioscorea fluribenda tubers

Abstract

The main goal of the current study was aimed to evaluate the binding efficacy of isolated starch form Dioscorea fluribenda tubers as a tablet binder. The isolated starch was subjected to determination of various physicochemical parameters as well identification test to characterize the quality and purity of starch. Morphology of the isolated starch was determined by quantitative microscopy and the other various physicochemical parameter studies were performed according to the Pharmacopoeial standard procedure. After characterization the isolated starch, it was subjected to formulation of tablet, taking Paracetamol as API and compared with marketed tablet formulation. Various quality control tests for evaluation of the tablets were performed according to Indian Pharmacopoeia. From the different experimental quality control standards it was concluded that isolated starch is comparable with industrial starch.