Comparative antipyretic activity of ethanolic extracts of some species of Cynodon in rabbits

Abstract

To investigate and compare the antipyretic activity of the Ethanolic extracts of Cynodon dactylon and Cynodon barberi in rabbits. The antipyretic activity of Ethanolic extract at a dose of 400 mg/kg and 600 mg/kg was tested be milk induced pyrexia in rabbits. Paracetamol (100 mg/kg) was used as standard drug and control group received distilled water. Rectal temperature of the rabbits was recorded till 4 hrs at an interval of 1 hr using digital thermometer. The investigation showed that the 600 mg/kg dose of both the drug showed a reasonable decrease in temperature (p