Antioxidant Activity and Antibacterial Activity of Walidda antidysentericay

Abstract

Traditional medical systems use plants in curing and preventing diseases as cancer, anti- aging, infections etc. Walidda antidysenterica is an endemic plant to Sri Lanka with many recoded traditional uses but yet to be investigated scientifically in detail. We investigated the antioxidant and antibacterial properties of the methanol extracts of Walidda antidysenterica leaves, seeds, trunk, bark and root. Antibacterial activity of the methanol extracts of Walidda antidysenterica determined using disk diffusion method against Methicillinsensitive Staphylococcus aureus (MSSA) (ATCC 25923), MethicillinresistantStaphylococcus aureus (MRSA) (Bench) showed the highest inhibition for leaves with zones of 22.9±0.2 and 23.6±0.4 mm against MSSA and MRSA respectively. The leaves showed the best antioxidant properties with a 65.77±1.99µg/ml, IC50 value for DPPH scavenging activity, total phenolic content of 32.56±1.08 and the best total reducing power of the extracts.