Studies on anticancer, haemolytic activity and chemical composition of crude epidermal mucus of fish Mugil cephalus

Abstract

The healthy live fish Mugil cephalus were purchased from lower Anaikkat in Kollidam River, Thanjavur District. Tamilnadu, India. Mucus was carefully scraped from the dorsal body using a sterile spatula, the collected fish mucus was stored separately at 4 °C for further use. Anticancer activity was done by laryngeal cancer cell lines. Primarily the hemolytic activity was done in chicken and goat blood erythrocytes were recorded. Further characterization of crude mucus was done through FT - IR.Studies on the anticancer activity of the skin mucus from Mugil cephalus has remarkable anticancer activity. The mucus sample showed absence of hemolytic activity in sheep and chick blood erythrocytes, FT-IR analyze revealed the presence of bioactive compounds signals at different ranges. Mugil cephalus mucus may also contain some biologically active agents which has anticancer activity and absence of hemolytic activity. In future, purification and structural identification of compounds will be carried out in mucus of fish Mugil cephalus.