Phenolic Compound, Free radical assay, Anti-microbial and Anti-fungal Investigation of Pterospermum semisagittatum: A Herbal Flora of Bangladesh

Abstract

The present study was on Pterospermum semisagittatum investigated for its phenolic content, free radical scavenging (DPPH) assay, Antimicrobial and fungal activity. The highest phenolic content was found in the pet ether (PESF) (4.25±0.08 mg) followed by carbon tetrachloride soluble partitionate (CTCSF) (2.70±0.27 mg), chloroform soluble partitionate (CSF) (0.56±0.29 mg), methanolic extract (ME) (2.41±0.14 mg) and aqueous soluble partitionate (AQSF) (1.67±0.06 mg). In free radical scavenging (DPPH) assay, methanolic extract (ME), carbon tetrachloride soluble partitionate (CTCSF), pet ether (PESF), chloroform soluble partitionate (CSF) and aqueous soluble partitionate AQSF respectively, IC50 was 121.50±0.71, 112.50±1.14, 102.50±0.65 and 53.50±2.12. In Anti-microbial and anti-fungal investigation only chloroform soluble partitionate observed the Slight amount of activity. This study profound that Pterospermum semisagittatum has the remarkable presence of phenolic and antioxidant compound on preliminary investigational evaluation.