review Open AccessTop 10% cited
Recent advances in epilepsy
Journal of Neurology · 2017 · Vol. 264(8) · pp. 1811–1824
Mark Manford✉(University of Cambridge)
Abstract
This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics and underlying mechanisms, including status epilepticus, drug and surgical treatments. Lessons from rarer epilepsies regarding the relationship between epilepsy type, mechanisms and choice of antiepileptic drugs (AED) are explored and data regarding AED use in pregnancy are reviewed. Concepts evolving towards a move from treating seizures to treating epilepsy are discussed, both in terms of the mechanisms of epileptogenesis, and in terms of epilepsy's broader comorbidity, especially depression.
Epilepsy research and treatmentPharmacological Effects and Toxicity StudiesNeuroscience and Neuropharmacology ResearchEpileptogenesisEpilepsyStatus epilepticusNeurologyMedicineComorbidityPsychiatryDrug Resistant EpilepsyIntensive care medicineNeuroscience
MeSH terms
AnimalsEpilepsyHumans
Citations
304
FWCI
9.64
field-weighted impact
References
197
Percentile
99%
vs. same field & year
Citations per year
References
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