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Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier

World Journal of Gastroenterology · 2017 · Vol. 23(1) · pp. 60–60

Da Zhou✉(XinHua Hospital)Qin Pan(XinHua Hospital)Feng‐Zhi Xin(XinHua Hospital)Rui-Nan Zhang(XinHua Hospital)Chong-Xin He(XinHua Hospital)Guangyu Chen(XinHua Hospital)Chang Liu(XinHua Hospital)Yuanwen Chen(XinHua Hospital)Jian‐Gao Fan(XinHua Hospital)

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Abstract

NaB may restore the dysbiosis of gut microbiota to attenuate steatohepatitis, which is suggested to be a potential gut microbiota modulator and therapeutic substance for NAFLD.

Gut microbiota and health Diet and metabolism studies Liver Disease Diagnosis and TreatmentGut floraSodium butyrateInternal medicineSteatohepatitisButyrateFatty liverEndocrinologyInflammationBiologyLiver injury

MeSH terms

Gastrointestinal MicrobiomeAnimalsDrug Evaluation, PreclinicalHumansImmunohistochemistryInflammationIntestinal MucosaLactobacillusLiverLiver Function TestsMaleMice, Inbred C57BLSpecific Pathogen-Free OrganismsTumor Necrosis Factor-alphaCytokines

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426

FWCI

12.31

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99%

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Role of the gut microbiota in type 2 diabetes and related diseases