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Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults

Gut · 2014 · Vol. 64(11) · pp. 1744–1754
Edward S. ChambersAlexander ViardotArianna PsichasDouglas J. MorrisonKevin G. MurphySagen Zac‐VargheseKenneth MacDougallTom PrestonCatriona TedfordGraham FinlaysonJohn E. BlundellJimmy D. BellE. Louise ThomasShahrul Mt‐IsaDeborah AshbyG. R. GibsonSofía KolidaWaljit S. DhilloStephen R. BloomWayne MorleyStuart CleggGary Frost

Abstract

NCT00750438.

Diet and metabolism studiesRegulation of Appetite and ObesityDietary Effects on HealthOverweightAppetiteMedicineBody weightPropionateWeight managementObesityInternal medicineEndocrinologyWeight loss

MeSH terms

MaleMiddle AgedBody Weight MaintenanceAppetite RegulationCells, CulturedColonDouble-Blind MethodFemaleHumansPropionatesCross-Over StudiesPeptide YYAdiposityOverweightGlucagon-Like Peptide 1

Funding

  • Wellcome Trust
  • National Institute for Health and Care Research
  • Imperial College London
  • Directorate for Biological Sciences
  • Medical Research Council
  • Biotechnology and Biological Sciences Research Council
  • National Health and Medical Research Council
  • NIHR Imperial Biomedical Research Centre
  • FP7 Health
Citations
1,348
FWCI
24.48
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