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Sleep, Cognitive impairment, and Alzheimer’s disease: A Systematic Review and Meta-Analysis

SLEEP · 2016 · Vol. 40(1)

Omonigho M. Bubu✉(University of South Florida)Michael Τ. Brannick(University of South Florida)James A. Mortimer(University of South Florida)Ogie Queen Umasabor‐Bubu(University of South Florida)Yuri V. Sebastião(University of South Florida)Yi Wen(University of South Florida)Skai Schwartz(University of South Florida)Amy R. Borenstein(University of South Florida)Yougui Wu(University of South Florida)David Morgan(USF Health Byrd Alzheimer's Institute)William Anderson(University of South Florida)

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Abstract

This meta-analysis confirmed the association between sleep and cognitive impairment or AD and, for the first time, consolidated the evidence to provide an "average" magnitude of effect. As sleep problems are of a growing concern in the population, these findings are of interest for potential prevention of AD.

Sleep and related disorders Sleep and Wakefulness Research Circadian rhythm and melatoninMeta-analysisPopulationCochrane LibraryMedicineRelative riskSleep (system call)CognitionConfidence intervalPsychiatryInternal medicine