reviewTop 1% cited

A polarizing question: do M1 and M2 microglia exist?

Nature Neuroscience · 2016 · Vol. 19(8) · pp. 987–991

Richard M. Ransohoff✉(Biogen (United States))

Neuroinflammation and Neurodegeneration Mechanisms Immune cells in cancer Immune Response and InflammationMicrogliaNeuroscienceZebrafishEpigenomicsBiologyTerminologyMacrophage polarizationComputational biologyMass cytometryPsychology

MeSH terms

AnimalsHumansLipopolysaccharidesMacrophagesPhenotypeCytokinesCell PolarityMicroglia

Citations

1,513

FWCI

77.24

field-weighted impact

References

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100%

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Citations per year

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References

Resting Microglia Directly Monitor the Functional State of Synapses<i>In Vivo</i>and Determine the Fate of Ischemic Terminals

Journal of Neuroscience · 2009 · 1,592 citations

Development, maintenance and disruption of the blood-brain barrier

Nature Medicine · 2013 · 2,385 citations

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life

Nature Neuroscience · 2007 · 1,582 citations

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

Neuron · 2012 · 3,978 citations

Microglia Modulate Wiring of the Embryonic Forebrain

Cell Reports · 2014 · 663 citations

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

Journal of Neuroscience · 2014 · 5,285 citations

ATP mediates rapid microglial response to local brain injury in vivo

Nature Neuroscience · 2005 · 3,942 citations

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

Nature Neuroscience · 2013 · 2,592 citations

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