articleTop 1% cited
Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo
Leukemia · 2015 · Vol. 30(2) · pp. 492–500
Daniel Sommermeyer✉(Fred Hutch Cancer Center)Michael Hudecek(Fred Hutch Cancer Center)Paula L. Kosasih(Fred Hutch Cancer Center)Tea Gogishvili(University of Würzburg)David G. Maloney(Fred Hutch Cancer Center)Cameron J. Turtle(Fred Hutch Cancer Center)Stanley R. Riddell(Institute for Advanced Study)
CAR-T cell therapy researchNanowire Synthesis and ApplicationsVirus-based gene therapy researchCytotoxic T cellChimeric antigen receptorCD8T cellIn vivoCD19BiologyImmunologyCell therapyAdoptive cell transfer
MeSH terms
AnimalsFemaleHumansImmunologic MemoryNeoplasmsReceptors, Antigen, T-CellRecombinant Fusion ProteinsCD4-Positive T-LymphocytesImmunotherapy, AdoptiveCD8-Positive T-LymphocytesMice
Funding
- Fred Hutchinson Cancer Research Center
Citations
832
FWCI
23.28
field-weighted impact
References
295
Percentile
100%
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