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The Pathophysiology of Tumor Necrosis Factors

Annual Review of Immunology · 1992 · Vol. 10(1) · pp. 411–452
P Vassalli

Abstract

Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More

Immune Cell Function and InteractionImmune Response and InflammationT-cell and Retrovirus StudiesBiologyEffectorPathophysiologyCD8NecrosisLineage (genetic)ImmunologyTumor necrosis factor alphaReceptorCancer research

MeSH terms

AnimalsHumansInfectionsInflammationNeoplasmsTumor Necrosis Factor-alpha
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