article Open AccessTop 1% cited
The impact of compliance with 6-hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis: a prospective observational study
Critical Care · 2005 · Vol. 9(6) · pp. R764–70
Fang Gao✉(Heart of England NHS Foundation Trust)Teresa Melody(Heart of England NHS Foundation Trust)Darren F Daniels(Good Hope Hospital)Simon Giles(Heart of England NHS Foundation Trust)Samantha Fox(Good Hope Hospital)
Abstract
Non-compliance with the 6-hour sepsis bundle was associated with a more than twofold increase in hospital mortality. Non-compliance with the 24-hour sepsis bundle resulted in a 76% increase in risk for hospital death. All medical staff should practise these relatively simple, easy and cheap bundles within a strict timeframe to improve survival rates in patients with severe sepsis and septic shock.
Sepsis Diagnosis and TreatmentNosocomial Infections in ICURespiratory Support and MechanismsMedicineSepsisInterquartile rangeSurviving Sepsis CampaignSeptic shockObservational studyProspective cohort studyEmergency medicinePneumoniaMortality rate
MeSH terms
AgedClinical ProtocolsCritical CareEnglandFemaleHumansMaleMiddle AgedOutcome and Process Assessment, Health CareProspective StudiesTime FactorsSurvival AnalysisHospital MortalitySepsisGuideline Adherence
Funding
- Eli Lilly and Company
Citations
463
FWCI
17.90
field-weighted impact
References
17
Percentile
100%
vs. same field & year
Citations per year
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References
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
Critical Care Medicine · 2001 · 8,573 citations
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference
Intensive Care Medicine · 2003 · 2,877 citations
Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock
New England Journal of Medicine · 2001 · 10,728 citations
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
Intensive Care Medicine · 2004 · 3,341 citations
Surviving Sepsis Campaign Management Guidelines Committee. Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
Critical Care Medicine · 2004 · 1,852 citations
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
Critical Care Medicine · 2004 · 3,039 citations
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