articleTop 1% cited
Physical stability enhancement of theophylline via cocrystallization
International Journal of Pharmaceutics · 2006 · Vol. 320(1-2) · pp. 114–123
A.V. Trask(University of Cambridge)W.D.S. Motherwell(Cambridge Crystallographic Data Centre)W. Jones✉(Pfizer (United Kingdom))
Crystallography and molecular interactionsCrystallization and Solubility StudiesEnergetic Materials and CombustionCocrystalTheophyllineCrystal engineeringHydrateCrystallizationChemistryOxalic acidMaterials scienceHydrogen bondOrganic chemistry
MeSH terms
Bronchodilator AgentsChemistry, PharmaceuticalCrystallizationDicarboxylic AcidsDrug StabilityFeasibility StudiesGlutaratesHydrogen BondingMaleatesMalonatesTheophyllineWaterMolecular StructureOxalic Acid
Funding
- Pfizer
Citations
548
FWCI
23.35
field-weighted impact
References
33
Percentile
100%
vs. same field & year
Citations per year
Cited by
Recent Advances in Understanding the Mechanism of Cocrystal Formation via Grinding
Crystal Growth & Design · 2009 · 725 citations
Applying Hot-Stage Microscopy to Co-Crystal Screening: A Study of Nicotinamide with Seven Active Pharmaceutical Ingredients
Crystal Growth & Design · 2008 · 343 citations
Hierarchy of Supramolecular Synthons: Persistent Carboxylic Acid···Pyridine Hydrogen Bonds in Cocrystals That also Contain a Hydroxyl Moiety
Crystal Growth & Design · 2008 · 469 citations
Pharmaceutical Cocrystals and Their Physicochemical Properties
Crystal Growth & Design · 2009 · 1,459 citations
Cambridge Structural Database Analysis of Molecular Complementarity in Cocrystals
Crystal Growth & Design · 2009 · 279 citations
Pharmaceutical cocrystals: along the path to improved medicines
Chemical Communications · 2015 · 902 citations
Mechanochemistry: opportunities for new and cleaner synthesis
Chemical Society Reviews · 2011 · 2,928 citations
Pharmaceutical cocrystals: An overview
International Journal of Pharmaceutics · 2011 · 642 citations
References
Analytical profiles of drug substances
Journal of Pharmaceutical Sciences · 1975 · 1,498 citations
Crystal Engineering of the Composition of Pharmaceutical Phases: Multiple-Component Crystalline Solids Involving Carbamazepine
Crystal Growth & Design · 2003 · 531 citations
Encoding and decoding hydrogen-bond patterns of organic compounds
Accounts of Chemical Research · 1990 · 4,564 citations
Systematic analysis of the probabilities of formation of bimolecular hydrogen-bonded ring motifs in organic crystal structures
New Journal of Chemistry · 1999 · 353 citations
Pharmaceutical Cocrystallization: Engineering a Remedy for Caffeine Hydration
Crystal Growth & Design · 2005 · 649 citations
Crystal engineering of the composition of pharmaceutical phases. Do pharmaceutical co-crystals represent a new path to improved medicines?
Chemical Communications · 2004 · 1,053 citations
Related articles
Pharmaceutical Cocrystallization: Engineering a Remedy for Caffeine Hydration
Crystal Growth & Design · 2005 · 649 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.