articleTop 1% cited
Recent Advances in Understanding the Mechanism of Cocrystal Formation via Grinding
Crystal Growth & Design · 2009 · Vol. 9(3) · pp. 1621–1637
Tomislav Friščić✉(University of Cambridge)William Jones(Pfizer (United Kingdom))
Abstract
A brief and systematic overview of recent advances in understanding the mechanism of mechanochemical cocrystallization at macroscopic (bulk phase transformations) and microscopic levels (molecular recognition) is given. The review particularly addresses neat and liquid-assisted grinding approaches to cocrystal formation.
Crystallography and molecular interactionsCrystallization and Solubility StudiesX-ray Diffraction in CrystallographyCocrystalGrindingMechanism (biology)MechanochemistryNanotechnologyMaterials scienceChemistryMetallurgyMoleculePhysics
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