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Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study

The Lancet Infectious Diseases · 2012 · Vol. 13(2) · pp. 137–146
A Sarah WalkerCamilla L. C. IpRuth HarrellJason T. EvansGeorgia KapataiMartin DedicoatDavid W. EyreDaniel J. WilsonPeter M. HawkeyDerrick W. CrookJulian ParkhillDavid HarrisA Sarah WalkerRory BowdenPhilip MonkE. Grace SmithTim Peto

Abstract

Medical Research Council, Wellcome Trust, National Institute for Health Research, and the Health Protection Agency.

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosisInfectious Diseases and TuberculosisBiologyOutbreakMycobacterium tuberculosisTuberculosisSingle-nucleotide polymorphismGeneticsGenomeDNA sequencingGenotypeVirology

MeSH terms

Cross-Sectional StudiesDisease OutbreaksUnited KingdomHumansGenetic LinkageLongitudinal StudiesMycobacterium tuberculosisRetrospective StudiesTuberculosis, PulmonaryCluster AnalysisConfidence IntervalsGenome, BacterialSequence Analysis, DNACommunity-Acquired InfectionsTandem Repeat Sequences

Funding

  • United Kingdom Clinical Research Collaboration
  • National Institute for Health and Care Research
  • Medical Research Council
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