review Open AccessTop 1% cited
Management Options for Reducing the Release of Antibiotics and Antibiotic Resistance Genes to the Environment
Environmental Health Perspectives · 2013 · Vol. 121(8) · pp. 878–885
Amy Pruden✉(Virginia Tech)D. G. Joakim Larsson(University of Gothenburg)Alejandro Amézquita(Unilever (United Kingdom))Peter Collignon(Australian National University)Kristian K. Brandt(University of Copenhagen)David W. Graham(Newcastle University)James M. Lazorchak(Environmental Protection Agency)Satoru Suzuki(Ehime University)P. Silley(University of Bradford)Jason Snape(AstraZeneca (United Kingdom))Edward Topp(Agriculture and Agri-Food Canada)Tong Zhang(City University of Hong Kong)Yong‐Guan Zhu(Chinese Academy of Sciences)
Abstract
Environmental releases of antibiotics and antibiotic-resistant bacteria can in many cases be reduced at little or no cost. Some management options are synergistic with existing policies and goals. The anticipated benefit is an extended useful life span for current and future antibiotics. Although risk reductions are often difficult to quantify, the severity of accelerating worldwide morbidity and mortality rates associated with antibiotic resistance strongly indicate the need for action.
Pharmaceutical and Antibiotic Environmental ImpactsChemistry and Chemical EngineeringAntibiotic Use and ResistanceAntibioticsAntibiotic resistanceMicrobiologyMedicineBiotechnologyBiologyIntensive care medicine
MeSH terms
AgricultureAnimal HusbandryAnti-Bacterial AgentsDecision MakingDrug Resistance, MicrobialEnvironmental MonitoringIndustrial WasteMedical WasteWaste Disposal, FluidWater Pollutants, ChemicalWater Pollution, ChemicalAquacultureWastewater
Citations
795
FWCI
24.63
field-weighted impact
References
92
Percentile
100%
vs. same field & year
Citations per year
Cited by
Using the class 1 integron-integrase gene as a proxy for anthropogenic pollution
The ISME Journal · 2014 · 1,270 citations
Concentrations of antibiotics predicted to select for resistant bacteria: Proposed limits for environmental regulation
Environment International · 2015 · 925 citations
A review of the global climate change impacts, adaptation, and sustainable mitigation measures
Environmental Science and Pollution Research · 2022 · 2,034 citations
References
Heavy use of prophylactic antibiotics in aquaculture: a growing problem for human and animal health and for the environment
Environmental Microbiology · 2006 · 2,276 citations
Landfill leachate treatment: Review and opportunity
Journal of Hazardous Materials · 2007 · 2,520 citations
Effect of Abolishment of the Use of Antimicrobial Agents for Growth Promotion on Occurrence of Antimicrobial Resistance in Fecal Enterococci from Food Animals in Denmark
Antimicrobial Agents and Chemotherapy · 2001 · 647 citations
Fate and Transport of Antibiotic Residues and Antibiotic Resistance Genes following Land Application of Manure Waste
Journal of Environmental Quality · 2009 · 820 citations
Antibiotic resistance and its cost: is it possible to reverse resistance?
Nature Reviews Microbiology · 2010 · 2,315 citations
Effluent from drug manufactures contains extremely high levels of pharmaceuticals
Journal of Hazardous Materials · 2007 · 1,540 citations
A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment
Chemosphere · 2006 · 3,279 citations
Aquaculture: global status and trends
Philosophical Transactions of the Royal Society B Biological Sciences · 2010 · 945 citations
Related articles
The role of antibiotics and antibiotic resistance in nature
Environmental Microbiology · 2009 · 676 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
