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Role of Genes and Environments for Explaining Alzheimer Disease

Archives of General Psychiatry · 2006 · Vol. 63(2) · pp. 168–168

Abstract

In the largest twin study to date, we confirmed that heritability for AD is high and that the same genetic factors are influential for both men and women. However, nongenetic risk factors also play an important role and might be the focus for interventions to reduce disease risk or delay disease onset.

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatmentsGenetic Associations and EpidemiologyHeritabilityTwin studyMonozygotic twinDiseaseDizygotic twinsDizygotic twinDementiaDemographyPsychologyPopulation

MeSH terms

AgedAged, 80 and overAlzheimer DiseaseDiseases in TwinsFemaleHumansMaleModels, GeneticPhenotypeRegistriesRisk FactorsSex FactorsSocial EnvironmentSwedenTwins, Dizygotic
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