articleTop 1% cited
Efficacy and safety results from the randomized controlled comparative study of adalimumab vs. methotrexate vs. placebo in patients with psoriasis (CHAMPION)
British Journal of Dermatology · 2007 · Vol. 158(3) · pp. 558–566
J.‐H. Saurat✉(Probity Medical Research)G Stingl(Hôpital Saint-Louis)Louis Dubertret(Hôpital Saint-Louis)Kim Papp(Hôpital Saint-Louis)Richard G. Langley(Hôpital Saint-Louis)J.‐P. Ortonne(Probity Medical Research)Kristina Unnebrink(Probity Medical Research)Martin Kaul(Hôpital Saint-Louis)A. Camez(Probity Medical Research)for the CHAMPION Study Investigators
Abstract
After 16 weeks, adalimumab demonstrated significantly superior efficacy and more rapid improvements in psoriasis compared with either methotrexate or placebo.
Psoriasis: Treatment and PathogenesisDermatology and Skin DiseasesAutoimmune Bullous Skin DiseasesChampionSAINTMedicineNiceHumanitiesLibrary scienceArtPolitical scienceArt historyLaw
MeSH terms
AdalimumabAdultAnti-Inflammatory AgentsAntibodies, MonoclonalDose-Response Relationship, DrugDouble-Blind MethodFemaleHumansMaleMethotrexatePsoriasisQuality of LifeTreatment OutcomeAntirheumatic AgentsAntibodies, Monoclonal, Humanized
Funding
- Abbott Laboratories
Citations
720
FWCI
14.30
field-weighted impact
References
30
Percentile
99%
vs. same field & year
Citations per year
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References
Adalimumab, a fully human anti–tumor necrosis factor α monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: The ARMADA trial
Arthritis & Rheumatism · 2003 · 1,756 citations
A global phase III randomized controlled trial of etanercept in psoriasis: safety, efficacy, and effect of dose reduction
British Journal of Dermatology · 2005 · 692 citations
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