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A global phase III randomized controlled trial of etanercept in psoriasis: safety, efficacy, and effect of dose reduction
British Journal of Dermatology · 2005 · Vol. 152(6) · pp. 1304–1312
Kim Papp✉(Probity Medical Research)Stephen K. Tyring(The University of Texas Health Science Center at Houston)M. Lahfa(Ludwig-Maximilians-Universität München)Jörg C. Prinz(Probity Medical Research)C.E.M. Griffiths(Ludwig-Maximilians-Universität München)Arline Nakanishi(Hôpital Saint-Louis)Ralph Zitnik(Probity Medical Research)P.C.M. van de Kerkhof(Hôpital Saint-Louis)the Etanercept Psoriasis Study Group
Abstract
Etanercept provided clinically meaningful benefit to patients with chronic plaque psoriasis, with no apparent decrease in efficacy after dose reduction.
Psoriasis: Treatment and PathogenesisDermatology and Skin DiseasesRheumatoid Arthritis Research and TherapiesSAINTMedicineLibrary scienceFamily medicineArt historyArt
MeSH terms
EtanerceptAdolescentAdultAgedAged, 80 and overDose-Response Relationship, DrugDouble-Blind MethodDrug Administration ScheduleFemaleHumansImmunoglobulin GImmunosuppressive AgentsInjections, SubcutaneousMaleMiddle Aged
Citations
692
FWCI
13.00
field-weighted impact
References
16
Percentile
99%
vs. same field & year
Citations per year
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References
The effect of severe psoriasis on the quality of life of 369 patients
British Journal of Dermatology · 2006 · 557 citations
Psoriasis causes as much disability as other major medical diseases
Journal of the American Academy of Dermatology · 1999 · 1,493 citations
A sharper Bonferroni procedure for multiple tests of significance
Biometrika · 1988 · 4,717 citations
A Randomized Trial of Etanercept as Monotherapy for Psoriasis
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