σ-Chelation-directed C–H functionalizations using Pd(<scp>ii</scp>) and Cu(<scp>ii</scp>) catalysts: regioselectivity, stereoselectivity and catalytic turnover

Abstract

Recent progress in sigma-chelation directed C-H functionalization from the authors' group is described to illustrate the challenges and opportunities in the development of synthetically-useful catalytic reactions involving C-H activation as the key step. Emphasis is placed on strategies for developing catalysis under mild conditions and controlling regio- and stereoselectivity.