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Acquired Antibiotic Resistance Genes: An Overview
Frontiers in Microbiology · 2011 · Vol. 2 · pp. 203–203
Angela H. A. M. van Hoek✉(National Institute for Public Health and the Environment)Dik Mevius(Wageningen University & Research)Beatriz Guerra(Federal Institute for Risk Assessment)Peter Mullany(Eastman Dental Hospital)Adam P. Roberts(Eastman Dental Hospital)H.J.M. Aarts(National Institute for Public Health and the Environment)
Abstract
In this review an overview is given on antibiotic resistance (AR) mechanisms with special attentions to the AR genes described so far preceded by a short introduction on the discovery and mode of action of the different classes of antibiotics. As this review is only dealing with acquired resistance, attention is also paid to mobile genetic elements such as plasmids, transposons, and integrons, which are associated with AR genes, and involved in the dispersal of antimicrobial determinants between different bacteria.
Antibiotic Resistance in BacteriaPharmaceutical and Antibiotic Environmental ImpactsBacteriophages and microbial interactionsMobile genetic elementsAntibiotic resistanceTransposable elementBiologyGenePlasmidAntibioticsGeneticsBacteriaComputational biology
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