review Open AccessTop 1% cited
IL-18: A TH1 -inducing, proinflammatory cytokine and new member of the IL-1 family
Journal of Allergy and Clinical Immunology · 1999 · Vol. 103(1) · pp. 11–24
Charles A. Dinarello✉(University of Colorado Health)
Inflammasome and immune disordersinterferon and immune responsesCell death mechanisms and regulationCytokineProinflammatory cytokineReceptorCell biologyChemistryBiologyChemokineBiochemistryImmunologyInflammation
MeSH terms
AnimalsHumansInterferon-gammaTh1 CellsInterleukin-18Mice
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816
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References
Biologic basis for interleukin-1 in disease
Blood · 1996 · 4,341 citations
Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist
Arthritis & Rheumatism · 1998 · 971 citations
Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function
Immunity · 1998 · 2,015 citations
Interleukin-12: A Proinflammatory Cytokine with Immunoregulatory Functions that Bridge Innate Resistance and Antigen-Specific Adaptive Immunity
Annual Review of Immunology · 1995 · 2,419 citations
Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants
Journal of Leukocyte Biology · 1998 · 561 citations
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