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The Cell Biology of Macrophage Activation
Annual Review of Immunology · 1984 · Vol. 2(1) · pp. 283–318
Abstract
Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More
Macrophage Migration Inhibitory FactorImmune Cell Function and InteractionImmune cells in cancerBiologyEffectorMacrophageLineage (genetic)CD8Cell biologyCell lineageImmunologyReceptorCell
MeSH terms
Mannose ReceptorAnimalsAntibody-Dependent Cell CytotoxicityHistocompatibility Antigens Class IIColony-Stimulating FactorsCytoskeletonHumansLactoferrinLymphokinesLysosomesMacrophage ActivationMacrophagesMitochondriaNeoplasmsNucleotidases
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References
Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.
Journal of Biological Chemistry · 1982 · 4,754 citations
Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.
The Journal of Experimental Medicine · 1983 · 1,949 citations
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