Biologically active products of stimulated liver macrophages (Kupffer cells)

Abstract

acid; IL, interleukin; LPS, lipopolysaccharide (endotoxin); LT, leukotriene; PAF, platelet-activating factor; PG, prostaglandin; PMA, phorbol 12-myristate 13-acetate; TNF, tumor necrosis factor z (cachectin); TX, thromboxanc.Enzymes.Acyl-CoA synthetase (EC 6.2.1.3);adenylate cyclase (EC 4.6.1 .I); angiotensin-converting enzyme (dipeptidyl carboxypeptidase I, EC 3.4.15.1); collagenase (EC 3.4.24.7); prostaglandin H synthase (cyclo-oxygenase; EC 1.13.11.-); diacylglyccrol lipase (EC 3.1.1.34);elastase (EC 3.4.21.37); epoxide hydrolase (EC 3.3.2.3); glucose-6-phosphate dehydrogenase (EC 1.1.1.49);glutathione S- transferase (EC 2.5.1.18);y-glutamyl transferase (EC 2.3.2.2); glycerol-3-phosphate dehydrogenase (EC 1 .I .I .8);lipoprotein lipase (EC 3.1.1.34);;lysolecithin acyltransferase (EC 2.3.1.23);lyso-PAF acetyltransferase (EC 2.3.1.-);lysozyme (EC 3.2.1.17);myeloperoxidase (EC 1.13.1.7);NADPH oxidase (EC 1.6.99.-); 6-phosphogluconate dehydrogenase (EC 1.1.1.44);phospholipase A2 (EC 3.1.1.4);phospholipasc C (EC 3.1.4.3); pronase (EC 3.4.24.--); prostaglandin-D2 synthase (EC 5.3.99.2); prostaglandin-E, synthase (EC 5.3.99.3); protein kinase C (EC 2.7.1.37);superoxide dismutase (EC 1.15.1.1);thromboxane synthase (EC 5.3.99.5).