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High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity

Gastroenterology · 2009 · Vol. 137(5) · pp. 1716–1724.e2
Marie A. HildebrandtChristian HoffmannScott Sherrill-MixSue A. KeilbaughMicah HamadyYingyu ChenRob KnightRexford S. AhimaFrederic D. BushmanGary D. Wu
Gut microbiota and healthDiet and metabolism studiesEpigenetics and DNA MethylationFirmicutesBiologyMicrobiomeBacteroidetesObesityGut floraGenotypePhenotypeProteobacteriaFeces

MeSH terms

AnimalsDietDietary FatsFemaleHormones, EctopicIntestinesMice, Inbred C57BLObesityRNA, Ribosomal, 16SMice, KnockoutIntercellular Signaling Peptides and ProteinsMiceMetagenome

Funding

  • University of Pennsylvania
  • National Institutes of Health
  • National Institute of Diabetes and Digestive and Kidney Diseases
Citations
1,589
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22.99
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References
Human gut microbes associated with obesity
Nature · 2006 · 8,677 citations
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
Proceedings of the National Academy of Sciences · 2007 · 4,550 citations
The gut microbiota as an environmental factor that regulates fat storage
Proceedings of the National Academy of Sciences · 2004 · 6,132 citations
MEGAN analysis of metagenomic data
Genome Research · 2007 · 3,436 citations
Prokaryotes: The unseen majority
Proceedings of the National Academy of Sciences · 1998 · 4,788 citations
The KEGG resource for deciphering the genome
Nucleic Acids Research · 2003 · 5,208 citations
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