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Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

Genes & Development · 2001 · Vol. 15(18) · pp. 2343–2360
Yi ZhangDanny Reinberg

Abstract

Department of Biochemistry and Biophysics, Curriculum in Genetics and Molecular Biology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, North Carolina 27599-7295, USA; Howard Hughes Medical Institute, Division of Nucleic Acids Enzymology, Department of Biochemistry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA

Epigenetics and DNA MethylationCancer-related gene regulationGenomics and Chromatin DynamicsBiologyHistone methylationHistoneHistone codeHistone methyltransferaseHistone H2AGeneticsTranscription (linguistics)Histone-modifying enzymesHistone H1

MeSH terms

Amino Acid SequenceAnimalsGene Expression RegulationHistonesHumansMolecular Sequence DataTranscription, GeneticSequence Homology, Amino AcidDNA Methylation

Funding

  • Howard Hughes Medical Institute
  • National Institutes of Health
Citations
1,506
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112
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References
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Nature · 2000 · 8,530 citations
TRANSCRIPTIONAL RESPONSES TO POLYPEPTIDE LIGANDS: The JAK-STAT Pathway
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