articleTop 10% cited
Rational Use of in Vitro P-glycoprotein Assays in Drug Discovery
Journal of Pharmacology and Experimental Therapeutics · 2001 · Vol. 299(2) · pp. 620–628
Joseph W. Polli✉(GlaxoSmithKline (United States))Stephen A. WringJoan E. HumphreysLili HuangJames P. MorganLindsey O. WebsterCosette S. Serabjit-Singh
Drug Transport and Resistance MechanismsProtein Interaction Studies and Fluorescence AnalysisAntibiotics Pharmacokinetics and EfficacyEffluxP-glycoproteinCalceinChemistryATPaseIn vitroBiochemistryPharmacologyBiologyEnzyme
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Passive Permeability and P-Glycoprotein-Mediated Efflux Differentiate Central Nervous System (CNS) and Non-CNS Marketed Drugs
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References
Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine*
Clinical Pharmacology & Therapeutics · 1997 · 683 citations
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