article Open AccessTop 1% cited
Prevention of Coronary Heart Disease with Pravastatin in Men with Hypercholesterolemia
New England Journal of Medicine · 1995 · Vol. 333(20) · pp. 1301–1308
James Shepherd✉(Glasgow Royal Infirmary)Stuart M. Cobbe(University of Glasgow)Ian Ford(University of Glasgow)Christopher IslesA R Lorimer(University of Glasgow)Peter W. Macfarlane(Glasgow Royal Infirmary)James H. McKillop(Glasgow Royal Infirmary)Christopher J. Packard(Glasgow Royal Infirmary)
Abstract
Treatment with pravastatin significantly reduced the incidence of myocardial infarction and death from cardiovascular causes without adversely affecting the risk of death from noncardiovascular causes in men with moderate hypercholesterolemia and no history of myocardial infarction.
Lipoproteins and Cardiovascular HealthStatistical Methods in Clinical TrialsHormonal and reproductive studiesPravastatinMedicineMyocardial infarctionCoronary heart diseaseInternal medicineCardiologyIncidence (geometry)Cholesterol
MeSH terms
Anticholesteremic AgentsCholesterolCoronary DiseaseDouble-Blind MethodHumansHypercholesterolemiaCholesterol, LDLMaleMiddle AgedMyocardial InfarctionNeoplasmsRiskIncidenceSurvival AnalysisPravastatin
Funding
- Bristol-Myers Squibb
Citations
7,469
FWCI
346.21
field-weighted impact
References
26
Percentile
100%
vs. same field & year
Citations per year
Cited by
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References
A Multiple Testing Procedure for Clinical Trials
Biometrics · 1979 · 3,326 citations
Pravastatin, lipids, and atherosclerosis in the carotid arteries (PLAC-II)
The American Journal of Cardiology · 1995 · 613 citations
Related articles
Prevention of Coronary Heart Disease with Pravastatin in Men with Hypercholesterolemia
New England Journal of Medicine · 1995 · 7,469 citations
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