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The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

Nature Structural & Molecular Biology · 2003 · Vol. 10(12) · pp. 1026–1032
Ji‐Joon SongJidong LiuNiraj H. ToliaJonathan SchneidermanStephanie K. SmithRobert A. MartienssenGregory J. HannonLeemor Joshua‐Tor
RNA Research and SplicingCRISPR and Genetic EngineeringRNA modifications and cancerArgonauteDicerRNA-induced silencing complexTrans-acting siRNASmall interfering RNARNA interferenceBiologyNucleic acidRNACell biology

MeSH terms

Amino Acid SequenceAnimalsBinding SitesCloning, MolecularDrosophila melanogasterModels, MolecularMolecular Sequence DataProtein ConformationRecombinant Fusion ProteinsRNASequence AlignmentSequence Homology, Amino AcidCrystallography, X-RayGene SilencingDrosophila Proteins
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The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes · Scinovex