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Purified Argonaute2 and an siRNA form recombinant human RISC

Nature Structural & Molecular Biology · 2005 · Vol. 12(4) · pp. 340–349
Fabiola V. RivasNiraj H. ToliaJi‐Joon SongJ.P. AragonJidong LiuGregory J. HannonLeemor Joshua‐Tor
RNA Interference and Gene DeliveryRNA Research and SplicingMicroRNA in disease regulationArgonauteEffectorRNA interferenceRecombinant DNASmall interfering RNABiologyCell biologyRNAMolecular biologyBiochemistry

MeSH terms

Adenosine TriphosphateAnimalsBase SequenceBinding SitesCell LineDrosophila melanogasterHumansKineticsModels, MolecularMolecular Sequence DataPeptide Initiation FactorsPhosphatesRecombinant ProteinsEukaryotic Initiation Factor-2Ribonuclease H
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773
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23.21
field-weighted impact
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54
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100%
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Citations per year
References
Kinetic analysis of the RNAi enzyme complex
Nature Structural & Molecular Biology · 2004 · 540 citations
RNA interference is mediated by 21- and 22-nucleotide RNAs
Genes & Development · 2001 · 3,295 citations
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