Scinovex
review Open AccessTop 1% cited

Systematic review: the role of the gut microbiota in chemotherapy‐ or radiation‐induced gastrointestinal mucositis – current evidence and potential clinical applications

Alimentary Pharmacology & Therapeutics · 2014 · Vol. 40(5) · pp. 409–421
Yann TouchefeuEmmanuel MontassierKristin M. NiemanThomas GastinneG. PotelStanislas Bruley des VarannesFrançoise Le VaconMarie France De La Cochetiere

Abstract

The gut microbiota may play a major role in the pathogenesis of mucositis through the modification of intestinal barrier function, innate immunity and intestinal repair mechanisms. Better knowledge of these effects may lead to new therapeutic approaches and to the identification of predictive markers of mucositis.

Oral health in cancer treatmentHead and Neck Cancer StudiesNeutropenia and Cancer InfectionsMucositisMedicineBifidobacteriumFaecalibacterium prausnitziiGut floraCancerChemotherapyGastroenterologyInternal medicineRadiation therapy

MeSH terms

AnimalsAntineoplastic AgentsDiarrheaHumansIntestinal DiseasesIntestinesNeoplasmsRadiation InjuriesProbioticsMucositisMicrobiota
Citations
410
FWCI
15.21
field-weighted impact
References
70
Percentile
99%
vs. same field & year
Citations per year
Cited by
Chemotherapy‐driven dysbiosis in the intestinal microbiome
Alimentary Pharmacology & Therapeutics · 2015 · 487 citations
References
Obesity alters gut microbial ecology
Proceedings of the National Academy of Sciences · 2005 · 6,096 citations
The VSL#3 probiotic formula induces mucin gene expression and secretion in colonic epithelial cells
American Journal of Physiology-Gastrointestinal and Liver Physiology · 2006 · 483 citations
Citation Network

How this paper connects to the literature. Drag to explore, click any node to open that paper.