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Dose–response relationship between alcohol consumption before and during pregnancy and the risks of low birthweight, preterm birth and small for gestational age (SGA)—a systematic review and meta‐analyses

BJOG An International Journal of Obstetrics & Gynaecology · 2011 · Vol. 118(12) · pp. 1411–1421

Jayadeep Patra✉(Centre for Addiction and Mental Health)Rachel Bakker(Erasmus University Rotterdam)Hyacinth Irving(Centre for Addiction and Mental Health)VWV Jaddoe(Erasmus University Rotterdam)Suttur S. Malini(Maharaja Krishna Chandra Gajapati Medical College and Hospital)Jürgen Rehm(Klinik und Poliklinik für Psychotherapie und Psychosomatik)

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Abstract

Dose-response relationship indicates that heavy alcohol consumption during pregnancy increases the risks of all three outcomes whereas light to moderate alcohol consumption shows no effect. Preventive measures during antenatal consultations should be initiated.

Prenatal Substance Exposure Effects Gestational Diabetes Research and Management Birth, Development, and HealthMedicineSmall for gestational agePregnancyGestational ageMeta-analysisObstetricsCINAHLAlcoholInternal medicine

MeSH terms

Alcohol DrinkingDose-Response Relationship, DrugFemaleHumansInfant, Low Birth WeightInfant, NewbornInfant, Small for Gestational AgePregnancyRegression AnalysisRiskRisk FactorsPremature Birth

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555

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37.59

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Cited by

The relationship between different dimensions of alcohol use and the burden of disease—an update