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Facile Oxidation of Aldehydes to Acids and Esters with Oxone

Organic Letters · 2003 · Vol. 5(7) · pp. 1031–1034
Benjamin R. TravisMeenakshi SivakumarG. Olatunji HollistBabak Borhan

Abstract

[reaction: see text] A highly efficient, mild, and simple protocol is presented for the oxidation of aldehydes to carboxylic acids utilizing Oxone as the sole oxidant. Direct conversion of aldehydes in alcoholic solvents to their corresponding ester products is also reported. These reactions may prove to be valuable alternatives to traditional metal-mediated oxidations.

Oxidative Organic Chemistry ReactionsTraditional and Medicinal Uses of AnnonaceaeAlkaloids: synthesis and pharmacologyChemistryAldehydeAlcohol oxidationOrganic chemistryMetalCombinatorial chemistryCatalysis
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