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Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid

Nature Structural & Molecular Biology · 2007 · Vol. 14(12) · pp. 1157–1164
Sandra ChimonMedhat A. ShaibatChristopher R. JonesDiana C CaleroBuzulagu AizeziYoshitaka Ishii
Alzheimer's disease research and treatmentsSupramolecular Self-Assembly in MaterialsProtein Structure and DynamicsFibrilChemistryAmyloid (mycology)Beta sheetNeurotoxicityP3 peptideBiophysicsBiochemistry of Alzheimer's diseaseProtein foldingPeptide

MeSH terms

AmyloidAnimalsFluorescent DyesHumansMicroscopy, FluorescenceModels, ChemicalNeurotoxinsPeptide FragmentsThiazolesAmyloid beta-PeptidesPC12 CellsProtein Structure, SecondaryProtein FoldingRatsBenzothiazoles

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  • National Science Foundation
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