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Design and Function of a Dendrimer-Based Therapeutic Nanodevice Targeted to Tumor Cells Through the Folate Receptor

Pharmaceutical Research · 2002 · Vol. 19(9) · pp. 1310–1316
Antonio Dı́az-QuintanaEwa RaczkaLars T. PiehlerInhan LeeAndrzej MycIstván MajorosAnil K. PatriThommey P. ThomasJames J. MuléJames R. Baker
Dendrimers and Hyperbranched PolymersRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesDendrimerNanodeviceFolate receptorDrug deliveryIntracellularTargeted drug deliverySurface modificationNanotechnologyNanomedicineBiophysics

MeSH terms

Carrier ProteinsDrug CarriersHumansReceptors, Cell SurfaceTumor Cells, CulturedDrug DesignDrug Delivery SystemsNanotechnologyFolate Receptors, GPI-Anchored

Funding

  • National Institutes of Health
  • National Cancer Institute
Citations
659
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References
Dendrimers:
Journal of Controlled Release · 2000 · 1,213 citations
Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitro
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1995 · 572 citations
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