articleTop 10% cited

Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitro

Biochimica et Biophysica Acta (BBA) - Biomembranes · 1995 · Vol. 1233(2) · pp. 134–144

Robert J. Lee(Purdue University West Lafayette)Philip S. Low✉(Purdue University West Lafayette)

Folate and B Vitamins Research Cancer, Lipids, and Metabolism Retinoids in leukemia and cellular processesLiposomeFolate receptorHeLaDoxorubicinCytotoxicityChemistryIn vitroPEG ratioTargeted drug deliveryEndocytosis

MeSH terms

Biological TransportCarrier ProteinsCytotoxinsDoxorubicinFolic AcidHumansLiposomesReceptors, Cell SurfaceTumor Cells, CulturedFolate Receptors, GPI-AnchoredIn Vitro Techniques

Citations

572

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11.64

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99%

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References

Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes

FEBS Letters · 1990 · 2,006 citations

Studies on the folic acid activity of human serum

Journal of Clinical Pathology · 1961 · 518 citations

Liposomes for the sustained drug release in vivo

Biochimica et Biophysica Acta (BBA) - Biomembranes · 1990 · 698 citations

Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential

Biochimica et Biophysica Acta (BBA) - Biomembranes · 1985 · 2,057 citations

Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo

Biochimica et Biophysica Acta (BBA) - Biomembranes · 1991 · 1,384 citations

Advances in targeting the folate receptor in the treatment/imaging of cancers

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