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Protein abundance profiling of the Escherichia coli cytosol

BMC Genomics · 2008 · Vol. 9(1) · pp. 102–102
Yasushi IshihamaThorsten SchmidtJuri RappsilberMatthias MannF. Ulrich HartlMichael J. KernerDmitrij Frishman

Abstract

Abundance measurements for more than 1000 E. coli proteins presented in this work represent the most complete study of protein abundance in a bacterial cell so far. We show significant associations between the abundance of a protein and its properties and functions in the cell. In this way, we provide both data and novel insights into the role of protein concentration in this model organism.

Advanced Proteomics Techniques and ApplicationsGenomics and Phylogenetic StudiesMass Spectrometry Techniques and ApplicationsBiologyProteomicsRibosomal proteinProteomeEscherichia coliComputational biologyBiochemistryIsobaric labelingFractionationQuantitative proteomics

MeSH terms

Chromatography, LiquidCytosolEscherichia coliMass SpectrometryEscherichia coli ProteinsProteomics

Funding

  • European Commission
  • Deutsche Forschungsgemeinschaft
  • Keio University
  • Eisai
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Protein abundance profiling of the Escherichia coli cytosol · Scinovex