articleTop 1% cited
Predicting transmembrane protein topology with a hidden markov model: application to complete genomes11Edited by F. Cohen
Journal of Molecular Biology · 2001 · Vol. 305(3) · pp. 567–580
Anders Krogh✉(Technical University of Denmark)B. Larsson(Technical University of Denmark)Gunnar von Heijne(Stockholm University)Erik L. L. Sonnhammer(Karolinska Institutet)
Machine Learning in BioinformaticsRNA and protein synthesis mechanismsGenomics and Phylogenetic StudiesMembrane topologyCaenorhabditis elegansTransmembrane proteinMembrane proteinNetwork topologyComputational biologyTransmembrane domainMarkov chainHidden Markov modelTopology (electrical circuits)
MeSH terms
AnimalsBacterial ProteinsFungal ProteinsMarkov ChainsMembrane ProteinsPlant ProteinsResearch DesignSensitivity and SpecificitySoftwareSolubilityReproducibility of ResultsGenomeProtein Structure, SecondaryPorinsComputational Biology
Funding
- Danmarks Grundforskningsfond
- Vetenskapsrådet
Citations
12,890
FWCI
74.52
field-weighted impact
References
45
Percentile
100%
vs. same field & year
Citations per year
Cited by
Novel genes for nitrite reductase and Amo‐related proteins indicate a role of uncultivated mesophilic crenarchaeota in nitrogen cycling
Environmental Microbiology · 2005 · 868 citations
Ecology of marine Bacteroidetes: a comparative genomics approach
The ISME Journal · 2013 · 731 citations
Statistical Analysis of Membrane Proteome Expression Changes in <i>Saccharomyces </i><i>c</i><i>erevisiae</i>
Journal of Proteome Research · 2006 · 1,073 citations
CHARMM-GUI<i>Membrane Builder</i>toward realistic biological membrane simulations
Journal of Computational Chemistry · 2014 · 2,673 citations
Phase Transfer Surfactant-Aided Trypsin Digestion for Membrane Proteome Analysis
Journal of Proteome Research · 2008 · 673 citations
Insights on Evolution of Virulence and Resistance from the Complete Genome Analysis of an Early Methicillin-Resistant <i>Staphylococcus aureus</i> Strain and a Biofilm-Producing Methicillin-Resistant <i>Staphylococcus epidermidis</i> Strain
Journal of Bacteriology · 2005 · 1,027 citations
Chitin metabolism in insects: structure, function and regulation of chitin synthases and chitinases
Journal of Experimental Biology · 2003 · 1,239 citations
Glycoproteomics Analysis of Human Liver Tissue by Combination of Multiple Enzyme Digestion and Hydrazide Chemistry
Journal of Proteome Research · 2009 · 398 citations
References
Topology prediction for helical transmembrane proteins at 86% accuracy–Topology prediction at 86% accuracy
Protein Science · 1996 · 605 citations
The detection and classification of membrane-spanning proteins
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1985 · 839 citations
Membrane protein structure prediction
Journal of Molecular Biology · 1992 · 1,673 citations
A tutorial on hidden Markov models and selected applications in speech recognition
Proceedings of the IEEE · 1989 · 22,616 citations
Transmembrane helices predicted at 95% accuracy
Protein Science · 1995 · 669 citations
Genome‐wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms
Protein Science · 1998 · 1,537 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.