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High Rates of Forward Transmission Events after Acute/Early HIV‐1 Infection

The Journal of Infectious Diseases · 2007 · Vol. 195(7) · pp. 951–959

Bluma Brenner(Jewish General Hospital)Michel Roger(Université de Montréal)Jean‐Pierre Routy(McGill University Health Centre)Daniela Moïsi(Jewish General Hospital)Michel Ntemgwa(Jewish General Hospital)Claudine Matte(Hôpital Notre-Dame)Jean‐Guy BarilRéjean ThomasDanielle Rouleau(Hôpital Notre-Dame)Julie Bruneau(Hôpital Saint-Luc)Roger LeBlancMario Legault(Fonds de Recherche du Québec - Santé)Cécile Tremblay(Hôtel-Dieu de Montréal)Hugues Charest(Institut National de Santé Publique du Québec)Mark A. Wainberg✉(Jewish General Hospital)Quebec Primary HIV Infection Study Group

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Abstract

Early infection accounts for approximately half of onward transmissions in this urban North American study. Therapy at early stages of disease may prevent onward HIV transmission.

HIV Research and Treatment HIV/AIDS Research and Interventions HIV/AIDS drug development and treatmentHuman immunodeficiency virus (HIV)Transmission (telecommunications)VirologyMedicineComputer scienceTelecommunications

MeSH terms

AdultDNA, ViralFemaleHumansMalePhylogenyQuebecRisk FactorsGenetic VariationHIV-1HIV InfectionsGenes, polDisease Transmission, InfectiousAnti-HIV AgentsDrug Resistance, Viral

Citations

650

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17.62

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100%

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Cited by

HIV-1 Transmission, by Stage of Infection