articleTop 1% cited

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

Gene · 2001 · Vol. 263(1-2) · pp. 103–112

Lisa Timmons(Carnegie Institution for Science)Donald L. Court(National Cancer Institute)Andrew Fire✉(Department of Embryology)

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CRISPR and Genetic Engineering Insect Resistance and Genetics Genetics, Aging, and Longevity in Model OrganismsRNA interferenceBiologyCaenorhabditis elegansRNA silencingMutantGeneticsPhenotypeGeneGene silencingFunction (biology)

MeSH terms

AnimalsBacteriaEscherichia coliFemaleFluorescenceLuminescent ProteinsMalePhenotypeRecombinant Fusion ProteinsRNA, Double-StrandedSpecies SpecificityTransfectionGene ExpressionCaenorhabditis elegansGene Transfer Techniques

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References

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Nature · 1998 · 15,183 citations

THE GENETICS OF <i>CAENORHABDITIS ELEGANS</i>

Genetics · 1974 · 15,324 citations

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

Journal of Molecular Biology · 1986 · 6,371 citations

RNA-triggered gene silencing

Trends in Genetics · 1999 · 619 citations

A complementation analysis of the restriction and modification of DNA in Escherichia coli

Journal of Molecular Biology · 1969 · 3,858 citations

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