articleTop 1% cited
Highly Enantioselective Conjugate Addition of Nitromethane to Chalcones Using Bifunctional Cinchona Organocatalysts
Organic Letters · 2005 · Vol. 7(10) · pp. 1967–1969
Benedek Vakulya✉(Hungarian Academy of Sciences)Szilárd Varga(Eötvös Loránd University)Antal Csámpai(Hungarian Academy of Sciences)Tibor Soós(Hungarian Academy of Sciences)
Abstract
Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.
Synthesis of heterocyclic compoundsAsymmetric Synthesis and CatalysisMulticomponent Synthesis of HeterocyclesNitromethaneChemistryEnantioselective synthesisBifunctionalCinchonaConjugateCinchona AlkaloidsOrganocatalysisOrganic chemistryAddition reaction
MeSH terms
CatalysisCinchonaCinchona AlkaloidsMethaneNitroparaffinsStereoisomerismThioureaMolecular StructureChalcones
Citations
976
FWCI
26.14
field-weighted impact
References
11
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100%
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References
Encoding and decoding hydrogen-bond patterns of organic compounds
Accounts of Chemical Research · 1990 · 4,564 citations
In the Golden Age of Organocatalysis
Angewandte Chemie International Edition · 2004 · 2,568 citations
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Highly Enantioselective Conjugate Addition of Nitromethane to Chalcones Using Bifunctional Cinchona Organocatalysts
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