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A complex secretory program orchestrated by the inflammasome controls paracrine senescence

Nature Cell Biology · 2013 · Vol. 15(8) · pp. 978–990

Juan Carlos Acosta✉(Hammersmith Hospital)Ana Banito(Hammersmith Hospital)Torsten Wüestefeld(University of Tübingen)Athena Georgilis(Imperial College London)Peggy Janich(Centre for Genomic Regulation)Jennifer P. Morton(Cancer Research UK Scotland Institute)Dimitris Athineos(Cancer Research UK Scotland Institute)Tae-Won Kang(University of Tübingen)Felix Lasitschka(German Cancer Research Center)Mindaugas Andrulis(Heidelberg University)Gloria Pascual(Centre for Genomic Regulation)Kelly J Morris(Imperial College London)Sadaf Khan(Imperial College London)Hong Jin(University of Leicester)Gopuraja Dharmalingam(Hammersmith Hospital)Ambrosius P. Snijders(Imperial College London)Thomas Carroll(Hammersmith Hospital)David Capper(German Cancer Research Center)Catrin Pritchard(University of Leicester)Gareth J. Inman(University of Dundee)Thomas Longerich(Heidelberg University)Owen J. Sansom(Cancer Research UK Scotland Institute)Salvador Aznar Benitah(Centre for Genomic Regulation)Lars Zender(University of Tübingen)Jesús Gil(Imperial College London)

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Telomeres, Telomerase, and Senescence Immune cells in cancer Neutrophil, Myeloperoxidase and Oxidative MechanismsParacrine signallingSenescenceCell biologyInflammasomeBiologyAutocrine signallingImmunologyCell cultureInflammationReceptor

MeSH terms

AnimalsColonic NeoplasmsHumansImmunohistochemistryInterleukin-1Protein BindingSignal TransductionGene Expression Regulation, NeoplasticCellular SenescenceParacrine CommunicationModels, AnimalCell Line, TumorMiceTransforming Growth Factor beta1Inflammasomes

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