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Intervertebral Disc Repair by Autologous Mesenchymal Bone Marrow Cells: A Pilot Study

Transplantation · 2011 · Vol. 92(7) · pp. 822–828

Lluís Orozco(Hospital Quirón Teknon)Robert SolerCarles MoreraMercedes Alberca(Instituto de Biomedicina y Genética Molecular de Valladolid)Ana Sánchez(Universidad de Valladolid)Javier García‐Sancho✉(Instituto de Biomedicina y Genética Molecular de Valladolid)

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Abstract

MSC therapy may be a valid alternative treatment for chronic back pain caused by degenerative disc disease. Advantages over current gold standards include simpler and more conservative intervention without surgery, preservation of normal biomechanics, and same or better pain relief.

Spine and Intervertebral Disc Pathology Musculoskeletal pain and rehabilitation Medical Imaging and AnalysisMedicineDegenerative disc diseaseIntervertebral discMesenchymal stem cellSurgeryBack painLow back painMagnetic resonance imagingDegeneration (medical)Lumbar

MeSH terms

AdultBiomechanical PhenomenaDisability EvaluationFeasibility StudiesFemaleHumansLumbar VertebraeMagnetic Resonance ImagingMalePain MeasurementPilot ProjectsQuality of Health CareTransplantation, AutologousTreatment OutcomeMesenchymal Stem Cell Transplantation

Citations

525

FWCI

17.22

field-weighted impact

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100%

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Cited by

Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells