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Treatment of Knee Osteoarthritis With Allogeneic Bone Marrow Mesenchymal Stem Cells

Transplantation · 2015 · Vol. 99(8) · pp. 1681–1690
Aurelio VegaMiguel Ángel Martín-FerreroFrancisco Del CantoMercedes AlbercaVerónica GarcíaAnna MunarLluís OrozcoRobert SolerJuan J. FuertesMarina HuguetAna SánchezJavier García‐Sancho

Abstract

Allogeneic MSC therapy may be a valid alternative for the treatment of chronic knee osteoarthritis that is more logistically convenient than autologous MSC treatment. The intervention is simple, does not require surgery, provides pain relief, and significantly improves cartilage quality.

Mesenchymal stem cell researchOsteoarthritis Treatment and MechanismsWound Healing and TreatmentsOsteoarthritisMedicineMesenchymal stem cellBone marrowStem cellPathologyBiologyCell biology

MeSH terms

AdultAgedCartilage, ArticularDisability EvaluationFemaleHumansInjections, Intra-ArticularKnee JointMagnetic Resonance ImagingMaleMiddle AgedPain MeasurementQuality of LifeSpainTime Factors
Citations
568
FWCI
26.47
field-weighted impact
References
46
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100%
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